To our knowledge, articles report results of small single-center studies, focus on specific components such as drug compatibilities, or reflect expert opinions. 12 However, empirical data on the handling of continuous infusions at the end of life in general hospital departments are still scarce, in particular internationally. 9, 11, 12 Errors in handling continuous infusions can result in serious adverse patient outcomes and pose a risk for patient safety, including life-shortening effects. 5, 9– 11 Moreover, existing literature indicates various challenges such as drug incompatibilities, difficulties with calculation of doses, and technical problems, for example, disconnection. 7, 8 This includes inadequate documentation, prescription without adequate indication, use of inappropriately high doses, and withholding of medication due to the fear of hastening death. 6 However, some reports, predominantly from the United Kingdom, raised concerns regarding misuse of continuous infusions in end-of-life care in general hospital departments. 2, 4, 5 Used correctly, continuous infusions are an appropriate and effective measure for symptom control. Several studies on medication at the end of life in general hospital departments suggest that drugs are frequently administered via continuous infusion in these circumstances. 2– 4 Because oral intake often becomes difficult at the end of life, alternative routes of administration are needed. 1 Opioids and sedatives are crucial for controlling these symptoms. Dying patients may suffer from symptoms such as pain, dyspnea, or agitation.
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